Kiran Infertility center is one of the best IVF center in Bangalore which
is providing world class treatment options like IVF, Test Tube Baby, ICSI,
Oocyte Donation, Embryo Donation, Oocyte/Embryo Freezing and Surrogacy.
In Vitro Fertilization (IVF)
In Vitro Fertilization is an assisted reproductive technology (ART)
commonly referred to as IVF. IVF is the process of fertilization by
extracting eggs, retrieving a sperm sample, and then manually combining
an egg and sperm in a laboratory dish. The embryo or embryos are then
transferred to the uterus through transvaginal route.
Why is IVF used ?
IVF can be used to treat infertility in the following cases :
Blocked or damaged fallopian tubes
Male factor infertility including decreased sperm count or sperm motility
Women with ovulation disorders, premature ovarian failure, uterine fibroids
Women who have had their fallopian tubes removed
Individuals with a genetic disorder
Preparing for IVF
Stimulation of Egg Growth
A woman having regular cycles will ovulate only one egg each month.
To increase the chance of obtaining pregnancy, an effort is made to recruit
as many eggs as possible. This goal is achieved by fertility drugs
(Gonal-F(R)). The growth and development of the eggs is closely monitored
by repeated ultrasound studies and blood tests for hormone levels (Estradiol
and Progesterone). Based on the information obtained from these tests, the
optimal timing for ovulation is determined. Ovulation itself is triggered
by an injection (Human Chorionic Gonadotropin), after which the egg
retrieval is scheduled.
Egg retrieval is scheduled about 36 hours after triggering ovulation
using HCG-Human Chorionic gonadotropin injection. The procedure itself
is performed at the hospital by a transvaginal route. A needle guided by
ultrasound imaging, is inserted through the vaginal wall into the ovaries,
where the follicles containing the eggs are punctured and aspirated.
The released eggs are transferred to the lab where their developmental
stage is assessed. General anesthesia is usually used for this simple
and minimally invasive day care procedure. The procedure takes about 10-15
minutes, and the patient can return home a few hours after it.
The IVF /In Vitro Fertilization procedure
Sperm is obtained by masturbation. It then undergoes a series of lab
procedures to prepare it for interaction with the egg. Eggs selected for
fertilization are kept in dishes to which sperm is added at the proper
concentration. The dishes are kept in an incubator where the environment
(temperature, humidity, gas composition) is carefully monitored. In given
time intervals the eggs are assessed for fertilization, and subsequent
divisions. The fertilized egg divides into two daughter cells, which
continue to divide rapidly as shown in the adjacent photographs. This
assessment is based on morphology.
Hence the detailed chromosomal composition of the embryos cannot be
addressed without further tests
Embryos that have satisfactorily divided are transferred to the uterus in
2-3 or maximum 5 days after fertilization. This simple and painless
procedure does not require sedation or anesthesia. The embryos are loaded
on a small plastic catheter, which is gently introduced through the cervix
into the uterus. Once in the uterine cavity, the embryos are gently released
and the catheter is withdrawn. The patient can return home after a couple
of hours of rest.
Generally, we recommend that following embryo transfer the patient should
refrain from physical exertion, however complete bed rest does is not
needed and in fact maybe counter affective. Just take it easy and hope for
good news. Given the nature of cycle stimulation, we prescribe medications
to support the young embryos hormonally. The presence of pregnancy is
established by using a sensitive test for Human Chorionic Gonadotropin
(HCG), which is the hormone secreted by the placenta. If pregnancy is
established, monitoring is continued, until ultrasound imaging allows a
direct visualization of the developing fetus and heart beat at day 28
following embryo transfer.
Advanced Artificial Reproductive Technology
Recent years have witnessed a rapid advancement in the treatment of the
“male factor infertility”, that is, those couples where the husband cannot
produce good quality sperm in the required concentration. Noble techniques
have been developed with which a single sperm is injected into the egg.
This procedure, referred to as ICSI (Intra Cytoplasmic Sperm Injection)
can accomplish fertilization with only minimal number of viable sperm.
ICSI has been one of the scientific finds of the century and has helped
millions of infertile couples from across the globe to become parents.
Website Link : https://kicbengaluru.com/